What Does Simparica Trio Cover?

Do you want to know What Does Simparica Trio Cover? Learn about the powerful veterinary medication that protects dogs against fleas, ticks, mites, and heartworm. Find out how the active ingredients Sarolaner, Moxidectin and Pyrantel work to keep your furry friend healthy and parasite-free. Don't miss this informative blog post

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Simparica Trio is a veterinary medication that is used to protect dogs against fleas, ticks, mites, and heartworm. It is a combination product that contains the active ingredients sarolaner, moxidectin, and pyrantel.

The power of Sarolaner, Moxidectin, and Pyrantel


Sarolaner is an isoxazoline class parasiticide, it works by binding to specific receptors in the nervous system of parasites such as fleas and ticks, causing paralysis and death.


Moxidectin is a macrocyclic lactone class parasiticidal drug which is used to treat and prevent heartworm, as well as to control various other internal and external parasites, like ear mites and demodectic mange mites.


Pyrantel is an anthelmintic, a medication that is used to treat parasitic worm infections. Specifically it acts as a depolarizing neuromuscular blocking agent, which means it causes temporary paralysis of the worms, that leads to their elimination from the gut after being excreted.

Understanding the distinctions: Fleas, Ticks, Mites, and Heartworm

Fleas, ticks, mites, and heartworm are all parasites that can infect dogs.


Fleas are small, wingless insects that feed on the blood of mammals and birds, including dogs. They can cause itching and discomfort for dogs, and can also transmit other parasites such as tapeworms.


Ticks are small, eight-legged arachnids that feed on the blood of mammals and birds, including dogs. They can transmit serious diseases such as Lyme disease and Rocky Mountain spotted fever.


Mites are small arthropods that can live on a dog’s skin or ears. Some types of mites, such as demodex mites, are normally present on a dog’s skin and do not cause problems. However, other types of mites, such as Sarcoptes scabiei, can cause a severe skin condition called mange.


Heartworm is a parasitic infection caused by a roundworm called Dirofilaria immitis. These worms live in the heart and blood vessels of the lung and can cause serious damage to the dog’s cardiovascular system if left untreated. They are transmitted by mosquitoes.

It’s important to note that Simparica Trio is a preventative medication to protect dogs against these parasite, but in case of infection, different treatment will be required, and it’s recommended to seek the help of a vet.


Simparica Trio is a powerful veterinary medication that is designed to protect dogs against fleas, ticks, mites, and heartworm. Given as a monthly chewable tablet, it is a convenient and easy way to keep your dog free from these harmful parasites. The tablet contains three active ingredients: sarolaner, moxidectin, and pyrantel, each one with a specific role to play in eliminating parasites and preventing future infestations.

It’s important to use Simparica Trio only as directed by a veterinarian, as they are the best qualified to determine the appropriate dosage and treatment plan for your dog based on their specific needs. Moreover, you can buy Simparica Trio in any retailers store that the veterinarian recommends, to make it more accessible for the dog owner.

As with any medication, it’s important to use it under the guidance and supervision of a veterinarian, to ensure that your dog receives the best possible care.

What Does Simparica Trio Cover

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