Does Simparica Trio Kill Tapeworms?

Discover if Simparica Trio effectively eliminates tapeworms with this informative guide. Get answers now.

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Simparica Trio is a popular and effective flea and tick medication for dogs. But does it also kill tapeworms? In this article, we will explore the efficacy of Simparica Trio in eliminating tapeworm infestations in dogs.

We will delve into the active ingredients, mode of action, and recommended dosage to provide you with a comprehensive understanding of this medication. So, let’s dive in and find out if Simparica Trio is the solution for tapeworms in dogs.

What is Simparica Trio?

Simparica Trio is a broad-spectrum parasiticide that provides protection against fleas, ticks, heartworms, roundworms, hookworms, and whipworms in dogs. It is a monthly chewable tablet that is highly effective in preventing and treating various parasitic infestations. Simparica Trio contains three active ingredients: sarolaner, moxidectin, and pyrantel. These ingredients work synergistically to target and eliminate different types of parasites.

Sarolaner: The Flea and Tick Killer

Sarolaner is the primary ingredient in Simparica Trio responsible for killing fleas and ticks. It belongs to the isoxazoline class of insecticides, which disrupts the nervous system of parasites, leading to their paralysis and subsequent death. Sarolaner starts working within hours of administration and provides continuous protection for up to 35 days, effectively preventing flea and tick infestations.

Moxidectin: The Heartworm Preventer

Moxidectin is an anthelmintic drug that belongs to the macrocyclic lactone family. It is highly effective in preventing heartworm disease by eliminating the immature stages of heartworm larvae transmitted through mosquito bites. Moxidectin also has activity against certain intestinal worms, including roundworms and hookworms.

Pyrantel: The Intestinal Worm Eradicator

Pyrantel is an anthelmintic agent that specifically targets intestinal parasites, such as roundworms and hookworms. It works by paralyzing the worms, causing them to lose their grip on the intestinal walls, and ultimately leading to their expulsion from the body through normal bowel movements. Pyrantel is fast-acting and provides immediate relief from intestinal worm infestations.

Does Simparica Trio Kill Tapeworms?

While Simparica Trio is highly effective against fleas, ticks, heartworms, roundworms, hookworms, and whipworms, it does not directly kill tapeworms. Tapeworms belong to a different class of parasites called cestodes, and Simparica Trio’s active ingredients do not have specific activity against them.

However, Simparica Trio indirectly helps in controlling tapeworm infestations. Fleas are the primary vectors for tapeworm transmission. When a dog ingests fleas during grooming or biting, it can become infected with tapeworms. By eliminating fleas with Simparica Trio, you significantly reduce the risk of tapeworm infestations in your dog.

To effectively treat tapeworms, a separate medication specifically targeting cestodes, such as praziquantel, is required. Your veterinarian can prescribe the appropriate deworming medication to eradicate tapeworms if your dog is diagnosed with an infestation.

Recommended Dosage for Simparica Trio

To ensure the maximum effectiveness of Simparica Trio and to provide comprehensive protection against various parasites, it is crucial to administer the correct dosage based on your dog’s weight. The recommended dosage is 0.91-1.81 mg/lb (2-4 mg/kg) of sarolaner, 0.023-0.046 mg/lb (0.05-0.1 mg/kg) of moxidectin, and 9.1-18.2 mg/lb (20-40 mg/kg) of pyrantel.

It is essential to follow your veterinarian’s instructions and administer the medication as directed. Do not exceed the recommended dosage, as it may lead to adverse effects. If you have any concerns or questions regarding the dosage or administration of Simparica Trio, consult your veterinarian for clarification.


Simparica Trio is a highly effective parasiticide that provides comprehensive protection against fleas, ticks, heartworms, roundworms, hookworms, and whipworms in dogs. While it does not directly kill tapeworms, it plays a crucial role in preventing tapeworm infestations by eliminating fleas, the primary vectors for transmission. To treat tapeworms specifically, a separate medication targeting cestodes is required. Always consult your veterinarian for the appropriate deworming treatment if your dog is diagnosed with a tapeworm infestation.

In summary, Simparica Trio is a valuable tool in protecting your furry friend from various parasites, but it is essential to understand its limitations and seek appropriate treatment when necessary.

does simparica trio kill tapeworms

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