NexGard vs Advantix: A Comprehensive Comparison

Compare NexGard vs Advantix to find the best flea and tick treatment for your pet.

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When it comes to protecting our beloved pets from pesky fleas and ticks, it’s essential to choose the right treatment. With so many options available, it can be overwhelming to make a decision. In this article, we will delve into the world of flea and tick treatments and compare two popular options: NexGard and Advantix. Both products have gained a significant reputation in the market, but which one is better suited for your furry friend? Let’s find out!

The Battle Begins: NexGard vs Advantix

What is NexGard?

NexGard is a chewable flea and tick treatment for dogs. It is a monthly oral medication that provides effective protection against fleas and ticks. The active ingredient in NexGard is afoxolaner, which kills fleas before they can lay eggs and eliminates ticks, including the American dog tick, black-legged tick, and Lone Star tick.

What is Advantix?

Advantix, on the other hand, is a topical treatment that comes in the form of drops. It is also a monthly treatment that protects dogs from fleas, ticks, mosquitoes, sandflies, and stable flies. The active ingredients in Advantix are imidacloprid and permethrin, which work together to repel and kill fleas, ticks, and other pests.

Effectiveness and Duration

NexGard’s Effectiveness and Duration

NexGard is highly effective in killing fleas and ticks. According to a study conducted by the manufacturer, it kills 100% of fleas within 24 hours and 100% of ticks within 48 hours of administration. The effects of NexGard last for a month, providing continuous protection against these parasites.

Advantix’s Effectiveness and Duration

Advantix is also known for its effectiveness in killing fleas and ticks. It starts working within 12 hours of application and kills 98-100% of fleas within 24 hours. The effects of Advantix last for a month, ensuring that your furry friend remains protected.

Safety Considerations

NexGard’s Safety Considerations

NexGard is generally considered safe for use in dogs. However, as with any medication, there are some precautions to keep in mind. NexGard should not be used in dogs with a history of seizures or neurologic disorders. It is also important to note that NexGard is specifically formulated for dogs and should not be used on other animals.

Advantix’s Safety Considerations

Advantix is also safe for use in dogs, but it is important to follow the instructions carefully. It should not be used on cats, as it contains permethrin, which can be toxic to them. Additionally, Advantix should not be used on dogs that are hypersensitive to the active ingredients or have a history of seizures.

Application and Convenience

NexGard’s Application and Convenience

NexGard’s chewable format makes it easy to administer to dogs. The tasty beef-flavored chew is usually well-accepted by dogs, making the process hassle-free. It does not require any specific handling precautions, and there is no need to separate treated dogs from children or other pets after administration.

Advantix’s Application and Convenience

Advantix is applied topically, making it convenient for pet owners. The treatment is applied directly to the skin, typically between the shoulder blades, ensuring that the active ingredients are distributed throughout the dog’s body. However, it is important to avoid contact with the eyes or mouth during application.

Additional Benefits

Additional Benefits of NexGard

Apart from its flea and tick protection, NexGard also provides additional benefits. It has been shown to help control infestations of the common mite species, Demodex canis. Moreover, NexGard is available in different sizes, making it suitable for dogs of various weights.

Additional Benefits of Advantix

Advantix offers more than just flea and tick protection. It repels and kills mosquitoes, sandflies, and stable flies, which can be a nuisance for dogs. This added protection is particularly beneficial for dogs in areas where these pests are prevalent.


When it comes to choosing between NexGard and Advantix, both products offer effective flea and tick protection for dogs. NexGard is a chewable option that is easy to administer, while Advantix is a topical treatment that provides additional protection against mosquitoes and other pests. Ultimately, the choice depends on your dog’s specific needs and preferences. Consult with your veterinarian to determine which product is the best fit for your furry friend.

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